Soluble CR1 derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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4353201, 435 692, 4352521, 43525233, 530380, C07H 2104, C12N 1512, C12N 1570, C07K 14705

Patent

active

058592237

ABSTRACT:
Soluble polypeptides are provided that comprise no more than three short consensus repeats (SCR) of Complement Receptor 1, and contain SCR3. DNA molecules encoding such soluble polypeptides, as well as methods, vectors and host cells, also are provided.

REFERENCES:
Krych, M. et. al., Proc. Natl. Acad. Sci., 88, Sites within the complement C3b/C4b receptor important for the specificity of ligand binding pp. 4353-4357 (1991).
Makrides et al. J. Biol. Chem. 267: 24754 1992).

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