Soluble complex former for the affinity specific separation of m

Details Soluble complex former for the affinity specific separation of m Soluble complex former for the affinity specific separation of m

1978-03-20

1980-06-10

Padgett, Benjamin R.

Compositions

Absorptive, or bindive, and chemically yieldive

23230R, 252299, 252408, 424 2, 422 56, B01D 1508, G01N 3108

Patent

active

042072000

ABSTRACT:
The invention provides soluble complex forming agents suitable for specific separation of macromolecular substances and particularly of such biopolymers as nucleic acids. These agents contain soluble polymers, such as polyethyleneglycols of a molecular weight between 200 and 40,000, dextran of a molecular weight of 3.times.10.sup.-3 to 3.times.10.sup.-6 and linear polyacrylamides; to these soluble polymers at least one base specific group for nucleic acids is covalently bound. The bonding can be achieved by esterification, grafting, copolymerization or copolycondensation.

REFERENCES:
patent: 2732382 (1956-01-01), Minsk et al.
patent: 3544484 (1970-12-01), Roth
patent: 3904373 (1975-09-01), Harper
patent: 4070912 (1978-01-01), McNaughton

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