Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Reexamination Certificate
2007-01-30
2007-01-30
Ewoldt, G. R. (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
C530S380000
Reexamination Certificate
active
10309611
ABSTRACT:
The present invention provides for the use of soluble forms of CD83 and nucleic acids encoding them for the treatment of diseases caused by the dysfunction or undesired function of a cellular immune response involving T cells. The invention moreover provides soluble CD83 molecules specifically suited for said purpose, antibodies against said specific soluble CD83 proteins and assay methods and kits comprising said antibodies.
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Lechmann, Matthias, et al; “The extracellular Domain of CD83 Inhibits Dendritic Cell-mediated T Cell Stimulation and Binds to a Ligand on Dendritic Cells”; J. Exp. Med. © The Rockefeller University Press; vol. 194, No. 12, Dec. 17, 2001; pp. 1813-1821.
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Lechmann Matthias
Steinkasserer Alexander
Zinser Elisabeth
Ewoldt G. R.
Norris McLaughlin & Marcus P.A.
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