Soluble and stable sources of tyrosine, cysteine and glutamine f

Details Soluble and stable sources of tyrosine, cysteine and glutamine f Soluble and stable sources of tyrosine, cysteine and glutamine f

1991-08-08

1993-04-27

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

A61K 3702

Patent

active

052062201

ABSTRACT:
The present invention provides soluble and/or stable sources of tyrosine, cysteine and glutamine for use in total parenteral nutrition (TPN), as well as a gradual release source of glutamic acid. In particular, these sources are gamma-glutamyltyrosine (.gamma.-GluTyr) gamma-glutamylcysteine derivatives (.gamma.-GluCys) and gamma-glutamylglutamine (.gamma.-GluGln). This invention provides TPN formulations, and methods of formulating and using such solutions containing .gamma.-GluTyr, .gamma.-GluCys and/or .gamma.-GluGln to provide adequate nutritional levels of tyrosine, cysteine or glutamine during TPN.

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Stehle et al. (1985) Nutr. Spec. Supp. 4: 116-123.
Stehle et al. (1988) J. Nutrition 118: 1470-1474.

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