Solubilizing agent of carbonated calcium hydroxide-based...

Dentistry – Method or material for testing – treating – restoring – or... – Endodontic

Reexamination Certificate

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C433S228100

Reexamination Certificate

active

06585514

ABSTRACT:

BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a solubilizing agent of a carbonated calcium hydroxide-based root canal filler, which is used for removal of a calcium hydroxide-based root canal filler having been carbonated and fixed to a root canal, from the root canal.
2. Description of the Conventional Art
In the dental remedy, as the remedy of pulp disease or apical periodontitis of teeth, a treatment for removing a sphacelus within a root canal or dentins on a stained root canal wall and a treatment for adjusting a root canal into a form wherein the root canal filling can be readily achieved, using an instrument such as a reamer and a file, are carried out simultaneously; and thereafter, a materially stable substance such as gutta-percha is filled within the root canal to seal a space within the root canal and shield an infectious route between the root canal and a periodontal tissue, or between the root canal and an oral cavity, thereby undergoing the root canal treatment.
Now, in order to achieve the root canal treatment, first of all, a dental pulp is removed, and root canal formation is then performed to enlarged a root canal, using an instrument such as a reamer and a file. Subsequently, the root canal is subjected to chemical cleaning by applying a chemical within the root canal after the enlargement. However, the root canal is complicated, and the number of root canals per tooth is different depending on a site at which the teeth are present. Namely, for example, a single root canal, two root canals, three root canals, or four root canals are present. Further, the shape of the root canal varies depending on the individual teeth, including a linear shape, a flat shape, and a curved shape. For these reasons, there may be a possibility that even when such a treatment is achieved, bacteria within the root canal cannot be removed completely, and therefore, even when the remedy is made to proceed, a toothache or a swelling of gingiva takes place by the infection of the remaining bacteria. In such case, it is necessary to carry out again the root canal treatment.
Thus, as a treatment for preventing this possibility from occurrence, root canal disinfection is taken. As this operation, employed is a process in which a calcium hydroxide-based root canal filler containing calcium hydroxide is filled temporarily within the root canal, thereby effecting disinfection utilizing a strong alkalinity of the calcium hydroxide. And, the following process is usually carried out. That is, after this treatment as the root canal disinfection has been completed, the root canal is washed with water, the moisture is removed, and a final root canal filler such as gutta-percha is then filled within the root canal.
The calcium hydroxide-based root canal filler has the following characteristics. That is, it not only has a soft effect rather than the strong transient sterilization effect, but also promotes the formation of a hard tissue by the matter that the calcium hydroxide is converted into calcium carbonate by carbon dioxide coming from a living body or the like, which is then fixed within the root canal, so that one can expect biological sealing of an apical foramen, and it is gentle to living bodies. These characteristics are ones never seen in other preparations. In the case where infectious diseases such as apical periodontitis unfortunately occur during the treatment of root canal disinfection with the calcium hydroxide-based root canal filler, it is necessary to surely remove the carbonated calcium hydroxide-based root canal filler reaching the root apex, eliminate the infected portion, and do the treatment with the chemical again. However, what the calcium hydroxide-based root canal filler having been gradually converted into calcium carbonate and fixed within the root canal is eliminated from the root canal having a complicated shape as described above by a mechanical cutting method with, for example, a reamer and a file, is a very difficult method and takes a long period of time. Also, there may be a possibility that infectious diseases such as inflammations again occur from a part of the infected portion that has not been eliminated within the root canal. Further, there may be a possibility that during cutting out by mechanical cutting with, for example, a reamer and a file, the root canal is cut out unnecessarily. Moreover, in many cases, the infection occurred during the root canal disinfection is caused by bacteria having been unable to be sterilized only by calcium hydroxide, or the like. In these cases, after removing the carbonated calcium hydroxide-based root canal filler, it is necessary to carry out another disinfection with, for example, an iodine preparation.
SUMMARY OF THE INVENTION
Under such background, the invention is aimed to provide a solubilizing agent of a carbonated calcium hydroxide-based root canal filler, by which during doing the root canal treatment again, the calcium hydroxide-based root canal filler that has been carbonated and fixed within a root canal can be surely eliminated from the root canal within a short period of time, and at the same time, the inside of the root canal can be sterilized.
In order to achieve the above-described aim, we, the present inventors made extensive and intensive investigations. As a result, it has been found that in order to remove a calcium hydroxide-based root canal filler, which after the root canal filling, has been gradually converted into calcium carbonate by carbon dioxide coming from a living body or the like and fixed on a root canal wall, when a solubilizing agent of a carbonated calcium hydroxide-based root canal filler, comprising water having a specific acid and a specific sterilizing properties-imparting agent compounded therewith, is used, the calcium carbonate can be readily dissolved within a short period of time, and at the same time, the inside of the root canal can be sterilized, leading to the accomplishment of the present invention.
Specifically, the solubilizing agent of the carbonated calcium hydroxide-based root canal filler according to the present invention comprises water containing at least one acid selected from the group consisting of phosphoric acid, gluconic acid, fumaric acid, lactic acid, glycolic acid, propionic acid, malic acid, maleic acid, citric acid, succinic acid, tartaric acid, acetic acid, glycerophosphoric acid, and malonic acid; and at least one sterilizing properties-imparting agent selected from the group consisting of an iodine preparation, a surfactant, a bactericide, hydrogen peroxide, and limonene. It is preferred that the amount of the at least one selected from the group consisting of phosphoric acid, gluconic acid, fumaric acid, lactic acid, glycolic acid, propionic acid, malic acid, maleic acid, citric acid, succinic acid, tartaric acid, acetic acid, glycerophosphoric acid, and malonic acid is 1 to 60% by weight of the whole; and that the amount of the at least one sterilizing properties-imparting agent selected from the group consisting of an iodine preparation, a surfactant, a bactericide, hydrogen peroxide, and limonene is 0.1 to 30% by weight of the whole.
DETAILED DESCRIPTION OF THE INVENTION
In the solubilizing agent of the carbonated calcium hydroxide-based root canal filler according to the present invention, the acid is used to dissolve the calcium hydroxide-based root canal filler that has been carbonated and fixed within the root canal and remove it. Since this acid is required to be safe against living bodies during the use within an oral cavity, the kind of the acid that can be used is, as a matter of course, limited. That is, from the viewpoint of the solubilizing agent of the carbonated calcium hydroxide-based root canal filler, a decalcification action against teeth should not be strong and an ability for reacting with calcium carbonate and dissolving it therein is required. The acid that can be used for the solubilizing agent of the carbonated calcium hydroxide-based root canal filler according to the present i

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