Solubilized topoisomerase poison agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S250000, C514S280000, C544S233000, C544S342000, C546S048000

Reexamination Certificate

active

06987109

ABSTRACT:
The invention provides compounds of formula I:whereinA, B, W, Y, Z, and R1have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.

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