Solubilized composition of poorly-soluble pharmaceutical product

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514 78, 514784, 514970, 514975, A61K 31685, A61K 4700

Patent

active

048660442

ABSTRACT:
3-(n-Octadecylcarbamoyloxy)-2-methoxypropyl 2-thiazolioethyl phosphate solubilized with use of a salt of salicyclic acid or/and a salt of a bile acid can be administered by stable injection without causing precipitation. A composition containing a reducing sulfur compound or a sequestering agent besides the above mentioned ingredients can be stored for a long term even at room temperature as well as a cold place.

REFERENCES:
patent: 3197368 (1965-07-01), Lappe et al.
patent: 4408052 (1983-10-01), Hozumi et al.
patent: 4582824 (1986-04-01), Nishikawa et al.
patent: 4681876 (1987-07-01), Marples et al.

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