Solubilized benzoyl peroxide and cosmetic solution including sol

Details Solubilized benzoyl peroxide and cosmetic solution including sol Solubilized benzoyl peroxide and cosmetic solution including sol

1989-01-25

1990-05-15

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 78, 424 62, A61K 700

Patent

active

049256661

ABSTRACT:
The solubilized benzoyl peroxide is made by mixing a heated combination of crystalline benzoyl peroxide with silicone glycol copolymer wherein the temperature of the mixture is in the range from 45.degree. to 65.degree. C. The benzoyl peroxide is no longer in crystallized form and hence the benzoyl peroxide is solubilized in the silicone glycol copolymer. The cosmetic solution includes a solubilized benzoyl peroxide as described above. Further, an independent mixture of alcohol, acetone and water is made. The solubilized benzoyl peroxide is then mixed with the second mixture (alcohol, acetone and water). The resulting cosmetic solution is very stable and the benzoyl peroxide remains in solution, i.e., an analysis of the cosmetic solution does not show any crystalline benzoyl peroxide. Further, primary irritation tests indicate this solution to be minimally irritating which is important for its use as a vehicle for topical application.

REFERENCES:
patent: 4478853 (1984-10-01), Chaussee

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