Solubilized benzoyl peroxide and cosmetic solution including sol

Details Solubilized benzoyl peroxide and cosmetic solution including sol Solubilized benzoyl peroxide and cosmetic solution including sol

1987-02-20

1989-08-15

Swisher, Nancy A.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

514714, A61K 4700

Patent

active

048573027

ABSTRACT:
The solubilized benzoyl peroxide is made by mixing a heated combination of crystalline benzoyl peroxide with silicone glycol copolymer wherein the temperature of the mixture is in the range from 45.degree. to 65.degree. C. The benzoyl peroxide is no longer in crystallized form and hence the benzoyl peroxide is solubilized in the silicone glycol copolymer. The cosmetic solution includes a solubilized benzoyl peroxide as described above. Further, an independent mixture of alcohol, acetone and water is made. The solubilized benzoyl peroxide is then mixed with the second mixture (alcohol, acetone and water). The resulting cosmetic solution is very stable and the benzoyl peroxide remains in solution, i.e., an analysis of the cosmetic solution does not show any crystalline benzoyl peroxide. Further, primary irritation tests indicate this solution to be minimally irritating which is important for its use as a vehicle for topical application.

REFERENCES:
patent: 4478853 (1984-10-01), Chaussee

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