Solubilization of ivermectin in water

Details Solubilization of ivermectin in water Solubilization of ivermectin in water

1981-09-21

1983-06-21

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424279, A61K 3170

Patent

active

043893970

ABSTRACT:
Ivermectin, an antiparasitic agent which is insoluble and unstable in water, is solubilized by the formation of colloidal particles, called micelles, with surface active agents as solubilizers and stabilized by using cosolvents and/or appropriate substrates in the aqueous formulation. The liquid formulations are suitable for use as parenteral or oral administration for the treatment of parasitic infections.

REFERENCES:
patent: 4093629 (1978-06-01), Fisher
patent: 4171314 (1979-10-01), Chabala et al.
patent: 4173571 (1979-11-01), Chabala et al.
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4200581 (1980-04-01), Fisher et al.
patent: 4201861 (1980-05-01), Mrozik et al.
patent: 4203976 (1980-05-01), Fisher et al.
patent: 4206205 (1980-06-01), Mrozik et al.
Chemical Abstracts, 86:34289s (1977), [Sato, T., et al., Japan. Kokai 76,112,509, 10/5/76].
Chemical Abstracts, 90:12219z (1979), [Burelova, A., et al., Farm. Obz. 1977, 46(2), 69-80].
Spiegel et al., Journal of Pharmaceutical Sciences, vol. 52, pp. 917-927 (1963).

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