Solubility of hydrophobic drugs with a compound having a...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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Reexamination Certificate

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07727556

ABSTRACT:
A pharmaceutical composition having improved solubility comprising a hydrophobic drug or pharmaceutically acceptable salt thereof and a compound having at least one carboxylic acid moiety, wherein the molar ratio of the compound having at least one carboxylic acid moiety to the hydrophobic drug or pharmaceutically acceptable salt thereof is from about 0.1:1 to about 25:1. The pharmaceutical composition exhibits rapid dissolution upon contact with physiological solvents, such as water, saliva or gastrointestinal fluids.

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Derwent Accession No. 2006-585625.
Written Opinion of the International Searching Authority.
Written Opinion of the International Searching Authority, Dated : Apr. 2006.

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