Solid tumor, cortical function, and nerve tissue imaging methods

Details Solid tumor, cortical function, and nerve tissue imaging methods Solid tumor, cortical function, and nerve tissue imaging methods

1992-06-08

1995-08-08

Pfaffle, Krista M.

Surgery

Truss

Pad

128654, 128664, 128665, 348 68, 348 77, 348164, 36441313, A61B 500, G01N 2100

Patent

active

054389895

ABSTRACT:
The present invention provides a method for imaging margins, grade and dimensions of solid tumor tissue located in an area of interest, comprising illuminating the area of interest with high intensity, emr (electromagnetic radiation) containing the wavelength of emr absorbed by a dye, obtaining a video signal of the area of interest as an averaged control image and processing the averaged control image into the averaged control frame, administering the dye by bolus injection into a vein circulating to the area of interest, obtaining a series of video images of the area of interest over time as subsequent images and processing each subsequent image as a subsequent frame, comparing each subsequent frame with the processed averaged control frame to obtain a series of difference images, and comparing each difference image for initial evidence of changed absorption within the area of interest which is the outline of solid tumor tissue, whereby tumor tissue is characterized by faster absorption of emr as a result of increased vascularity of solid tumor tissue and inability to clear the dye as fast as normal tissue.

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