Solid surface coated with a hydrophilic biopolymer-repellent out

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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525 5421, 525 5423, 525 5426, 525 5424, 525 5431, 525 60, 525 57, C08G 6900

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active

052409945

ABSTRACT:
A solid surface having anionic groups capable of reacting with a polyethylene imine substituted at least in part by at least 50% by weight of a hydrophilic nonionic polymer having a molecular weight within the range from about 400 to about 200,000 is provided with a hydrophilic biopolymer-repellent outer surface layer thereof by reacting such a polyethylene imine substituted by nonionic hydrophilic polymer with anionic groups on the solid surface, in an amount sufficient to produce biopolymer-repellent solid surface, and accordingly having low spontaneous adsorption of proteins and other biopolymers through electrostatic attraction and/or hydrophobic interaction.

REFERENCES:
patent: 4794002 (1988-12-01), Henis et al.
Kiss et al., article entitled "Surface grafting of polyethylneneoxide optimized by means of ESCA in Pogr. Colloid & Polymer Sci." 74:113-119 (1987).
Nikita in "The Chemistry of Cellulose and Wood", Ch IV, pp. 62-71 (1966) Jerusalem, S. Monson.

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