Solid support having ligand immobilized thereon by using...

Chemistry: analytical and immunological testing – Oxygen containing – Molecular oxygen

Reexamination Certificate

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C436S006000, C435S007100, C435S287200

Reexamination Certificate

active

07456022

ABSTRACT:
The present invention provides a method of analyzing the interaction between a ligand and a target molecule, which uses a solid support wherein the ligand is immobilized via a linker cleavable by photoirradiation, particularly a method of searching and purifying a target molecule. By intervening a linker specifically cleavable by photoirradiation between the ligand molecule and the solid support, release and elution of the target molecule from the solid support without using a ligand or salt at a high concentration can be enabled, and suppression of release and elution of a nonspecific protein can be enabled.

REFERENCES:
patent: 6057096 (2000-05-01), Rothschild et al.
patent: 6465628 (2002-10-01), Ravikumar et al.
patent: 2002/0168644 (2002-11-01), Aebersold et al.
patent: 2003/0027140 (2003-02-01), Ju et al.
patent: 2004/0265810 (2004-12-01), Aebersold et al.
patent: WO 02/079519 (2002-10-01), None
patent: WO 02/093131 (2002-11-01), None
Gygi, Steven P. et al., Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Oct. 1999, Nature Biotechnology, vol. 17, pp. 994-999.
Cano et al.,J. Org. Chem, 67(1): 129-135 (2002).
Enders et al.,Tetrahedron Letters, 45: 2839-2841 (2004).
Holmes et al.,J. Org. Chem., 60(8): 2318-2319 (1995).
Horton et al.,Tetrahedron Letters, 41: 9181-9184 (2000).
Kessler et al.,Organic Letters, 5(8): 1179-1181 (2003).
Tamura et al.,Bioconjugate Chem., 14(6): 1222-1230 (2003).

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