Solid, storage-stable, germicidal, pre-iodine composition

Details Solid, storage-stable, germicidal, pre-iodine composition Solid, storage-stable, germicidal, pre-iodine composition

1991-03-29

1993-08-03

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514728, 514731, 424667, 424668, 424669, A61K 3318

Patent

active

052329143

ABSTRACT:
A solid, storage-stable, germicidal, pre-iodine composition comprises in dry admixture with each other a solid oxy-compound of iodine, a solid reducing agent for the oxy-compound of iodine, and a solid desiccant used in amount sufficient to combine during the storage cycle of the composition with ambient and/or endogenous water. The oxy-compounds of iodine are iodic acid, iodine pentoxide, potassium iodate and sodium iodate. Preferred reducing agents are ascorbic acid, dihydroxy fumaric acid, the thiol sugars and cysteine. A preferred combination desiccant and iodine solvating agent is polyvinyl pyrrollidone having a molecular weight of from 10,000 to 1,000,000.
The composition is storage-stable for an indefinite period. Upon the addition of water, the oxy-compound of iodine is reduced to nascent iodine, which, in application, serves its well-known germicidal function.

REFERENCES:
patent: 1661640 (1928-03-01), Van Allen
patent: 4320114 (1982-03-01), Denzinger et al.
patent: 4321257 (1982-03-01), Sipos
De Gruyter, Concise Encyclopedia of Biochemistry, 1983; Walter de Gruyter & Co. Berlin 30, pp. 505-506.

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