Solid state NMR method with inverse detection

Details Solid state NMR method with inverse detection Solid state NMR method with inverse detection

2005-01-04

2005-01-04

Shrivastav, Brij B. (Department: 2859)

Electricity: measuring and testing

Particle precession resonance

Using a nuclear resonance spectrometer system

C324S309000

Reexamination Certificate

active

06838878

ABSTRACT:
A solid-state nuclear magnetic resonance (NMR) method for investigating a sample material, which contains protons H and also spin-1/2 hetero nuclei X, uses a sample material rotated at the magic angle. The method comprises the steps of increasing the equilibrium polarization of X; eliminating (2) proton magnetization; transferring polarization from X to H; and recording the proton signals (8) under a condition of line narrowing. A radio frequency (RF) pulse sequence effects polarization transfer between X and the closest protons H, via dipole coupling with coupling constant DXH. A parameter, which is associated with the transfer process, is varied to determine the dipole coupling constant DXHand thereby permits precise determination of the binding separation X—H, even when the concentration of X is small compared to H.

REFERENCES:
patent: 5117186 (1992-05-01), Burum et al.
patent: 5245284 (1993-09-01), Burum et al.
patent: 5926023 (1999-07-01), De Groot et al.
patent: 6027941 (2000-02-01), Jarvie et al.
patent: 6184683 (2001-02-01), Emsley et al.
patent: 6653832 (2003-11-01), Wind et al.
patent: 6670811 (2003-12-01), Wind et al.
patent: 6674282 (2004-01-01), Pines et al.
patent: 20030210046 (2003-11-01), Wind
Mueller, L.J. Am. Chem. Soc, 1979, 101, 4481-4484.
Bodenhausen, G.; Ruben, D.J. Chem. Phys. Lett., 1980, 69, 185-189.
Bax, A.; Griffey, R. R.; Hawkins, B. L.J. Magn. Reson. 1983, 55, 301-315.
Ishii, Y.; Tycko, R.J. Magn. Reson. 2000, 142, 199-204.
Schnell, I.; Langer, B.; Soentjens, S. H. M.; van Genderen, M. H. P.; Sijbesma, R. P.; Spiess, H. W.J. Magn. Reson.2001, 150, 57-70.
Goward, G. R.; Schnell, I.; Brown, S. P.; Spiess, H. W.; Kim, H.-D.; Ishida, H.Magn. Reson. Chem. 2001, 39, S5-S17.
Ishii, Y.; Yesinowski, J. P.; Tycko, R.J. Am. Chem. Soc. 2001, 123, 2921-2922.
Schmidt-Rohr, K.; Saalwaechter, K.; Liu, S.-F.; Hong, M.J. Am. Chem. Soc. 2001, 123, 7168-7169.
Hong, M.; Yamaguchi, S.J. Magn. Reson. 2001, 150, 43-48.
Sattler, M.; Schleucher, J.; Griesinger,C. Progr. NMR Spectr. 1999, 34, 93-158.
Saalwaechter, K.; Graf, R.; Spiess, H. W.J. Magn. Reson. 2001, 148, 398-418.
Zhao, X.; Sudmeier, J. L.; Bachovchin, W. W.; Levitt, M. H.J. Am. Chem. Soc. 2001, 123, 11097-11098.
Morris, G. A.; Freeman, R.J. Am. Chem. Soc. 1979, 101, 760-761.
Hing, A. W.; Vega, S.; Schaefer, J.J. Magn. Reson. 1992, 96, 205-209.
Graf, R.; Demco, D. E.; Gottwald, J.; Hafner, S.; Spiess, H. W.J. Chem. Phys. 1996, 106, 885-895.
Brown, S. P.; Schnell, I.; Brand, J. D.; Muellen, K.; Spiess, H. W.J. Am. Chem. Soc. 1999, 121, 6712.
Brown, S. P.; Zhu, X. X.; Saalwaechter, K.; Spiess, H. W.J. Am. Chem. Soc. 2001, 123, 4275-4285.
Schnell, I.; Spiess, H. W.J. Magn. Reson. 2001, 151, 153.
Fuess, H.; Hohlwein, D.; and Mason, S. A.Acta Cryst. 1977, B33, 654-659.
Fyfe, C. A.; Lewis, A. R.J. Phys. Chem. B 2000, 104, 48-55.
Bruno Alonso and Dominique Massiot; “Multi-scale NMR characterisation of mesostructured materials using 11-H-C through-bond polarisation transfer, fast MAS, and 1-H spin diffusion”; Journal of Magnetic Resonance, academic press, Orlando, FL, US Aug. 2003.
Pierre Reinheimer, Jerome Hirschinger, Pierre Granger, Philippe Breton, Alain Lagrange, Patrick Gilard, Marc Andree Lefebvre, and Noel Goetz, Cross-polarization/magic-angle-spinning nuclear magnetic resonance in selectively 13-C-labeled synthetic eumelanins; general subjects, Elsevier Science publishers, NL Oct. 1999.

Affiliated with

Also associated with

Rating

Solid state NMR method with inverse detection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Solid state NMR method with inverse detection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Solid state NMR method with inverse detection will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3374996