Solid shaped articles

Details Solid shaped articles Solid shaped articles

1986-04-08

1988-07-19

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Peptide containing

424400, 424464, 424484, A61K 4700, A61K 926, B65D 8556

Patent

active

047585986

ABSTRACT:
Solid shaped articles, particularly pharmaceutical dosage forms, are prepared by freezing in a mould a composition comprising a predetermined amount of chemical (e.g. pharmaceutical) and a solution of carrier material and then subliming solvent from the frozen composition. The side wall or walls of the mould make an angle with the vertical of at least 5.degree. at the surface of the composition. This enables shaped articles of constant thickness to be produced with minimum sublimation times.

REFERENCES:
patent: 4305502 (1981-12-01), Gregory et al.
patent: 4371516 (1983-02-01), Gregory et al.

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