Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1995-04-06
2000-02-29
Berch, Mark L
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
C07D50318, C12P 1718, A61K 3142
Patent
active
060310936
ABSTRACT:
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulanic acid has the formula (I): ##STR1## In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of .beta.-lactam antibiotics against many .beta.-lactamase producing bacteria.
REFERENCES:
patent: 4526783 (1985-07-01), Cole et al.
Cole Martin
Howarth Thomas T
Reading Christopher
Berch Mark L
Kinzig Charles M.
SmithKline Beecham p.l.c.
Williams Janice E.
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