Solid phase synthesizer

Details Solid phase synthesizer Solid phase synthesizer

1996-01-30

1998-04-28

Bhat, Nina

Chemical apparatus and process disinfecting, deodorizing, preser

Chemical reactor

Organic polymerization

422134, 530333, 530334, C08F 200

Patent

active

057441022

ABSTRACT:
Solid phase synthesizer and method of use for synthesis of a polymer. The synthesizer has a generally horizontal elongated vessel for holding a solid support and liquid having two ends, each end having a porous blocker to prevent the solid support from leaving the vessel but allowing passage of the liquid from the vessel. A particulate solid support is held within the vessel and has a size sufficient to prevent passage through the blocker.

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Seliger, "Ch. 17--Scale-Up of Oligonucleotide Synthesis," Methods in Molecular Biology 20, Protocols for Oligonucleotides and Analogs, S. Agrawal ed., Humana Press, Totowata, New Jersey, pp. 391-392 (1993).
Sinha, "Ch. 18--Large Scale Oligonucleotide Synthesis Using the Solid Phase Approach," Methods in Molecular Biology 20, Protocols for Oligonucleotides and Analogs, S. Agrawal ed., Humana Press, Totowata, New Jersey, pp. 440-442 (1993).

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