Solid-phase reactions

Details Solid-phase reactions Solid-phase reactions

2007-12-04

2007-12-04

Strzelecka, Teresa E. (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C536S023100, C536S024300

Reexamination Certificate

active

10269222

ABSTRACT:
The present invention relates to systems, compositions, and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for attaching nucleic acids to solid supports and modifying nucleic acids. For example, in some embodiments, the 5′ nuclease activity of a cleavage agent is used to cleave a cleavage structure formed on the solid support, the occurrence of the cleavage event indicating the presence of specific nucleic acid sequences.

REFERENCES:
patent: 5846717 (1998-12-01), Brow et al.
patent: 5985557 (1999-11-01), Prudent et al.
patent: 5994069 (1999-11-01), Hall et al.
patent: 6001567 (1999-12-01), Brow et al.
patent: 6060288 (2000-05-01), Adams et al.
patent: 6090543 (2000-07-01), Prudent et al.
patent: 6194149 (2001-02-01), Neri et al.
patent: 6348314 (2002-02-01), Prudent et al.
patent: 6372424 (2002-04-01), Brow et al.
patent: 6458535 (2002-10-01), Hall et al.
patent: 6500622 (2002-12-01), Bruchez et al.
patent: 6548021 (2003-04-01), Church et al.
patent: 6692917 (2004-02-01), Neri et al.
patent: 2003/0104470 (2003-06-01), Fors et al.
patent: 2004/0018491 (2004-01-01), Gunderson et al.
patent: WO 97/27214 (1997-07-01), None
patent: WO 98/15267 (1998-04-01), None
patent: WO 98/42873 (1998-10-01), None
patent: WO 98/50403 (1998-11-01), None
Maskos et al. oligonucleotide hybridization on glass supports: a novel linker for oligonucleotide synthesis and hybridization properties of oligonucleotides synthesized in situ. Nucleic acid Research, vol. 20, No. 7, pp. 1679-1684, Apr. 1992.
Fors et al. large-scale SNP scoring from unamplified genomic DNA. Pharmacogenomics. vol. 1, No. 2, pp. 219-229, May 2000.
Sojka et al. Evaluating the quality of oligonucleotides that are immobilized on glass supports for biosensor development. Analytica Chimica Acta. vol. 395, pp. 273-284, 1999.
Griffin et al. Direct genetic analysis by matrix-assisted laser desorption/ionization mass spectrometery. Proc, Natl. Acad. sci. USA, vol. 96, pp. 6301-6306, May 1999.
Griffin et al. PNAS, vol. 96, pp. 6301-6306, May 1999.
Fors et al. Pharmacogenomics, vol. 1, No. 2, pp. 219-229, May 2000.
Maskos et al. Nucleic acids Research, vol. 20, No. 7, pp. 1679-1684, 1992.
Sojka et al. Analytica Chimica Acta, vol. 395, pp. 273-284, 1999.
Kremsky, J.N. et al., “Immobilization of DNA via oligonucleotides containing an aldehyde or carboxylic acid group at the 5′ terminus”, Nucl. Acids Res., vol. 15, pp. 2891-2909 (1987).
Brookes, A. J., “The essence of SNPs”, Gene, vol. 234, pp. 177-186 (1999).
Nolan, J.P. et al., “The emergence of flow cytometry for sensitive, real-time measurements of molecular interactions”, Nature Biotechnol., vol. 16, pp. 633-638 (1998).
U.S. Appl. No. 09/723,622, filed Dec. 8, 2000, Neri et al.
Lyamichev et al., Nat. Biotech., 17:292 (1999).
Hall et al., PNAS, USA, 97:8272 (2000).
Agarwal et al., Diagn. Mol. Pathol. 9:158 [2000].
Cooksey et al., Antimicrob. Agents Chemother. 44:1296 [2000].
Griffin and Smith, Trends Biotechnol., 18:77 [2000].
Griffin and Smith, Analytical Chemistry 72:3298 [2000].
Hessner et al., Clin. Chem. 46:1051 [2000].
Ledford et al., J. Molec. Diagnostics 2,:97 [2000].
Lyamichev et al., Biochemistry 39:9523 [2000].
Mein et al., Genome Res., 10:330 [2000].
Neri et al., Advances in Nucleic Acid and Protein Analysis 3826:117 [2000].
Fors et al., Pharmacogenomics 1:219 [2000].
Griffin et al., Proc. Natl. Acad. Sci. USA 96:6301 [1999].
Kwiatkowski et al., Mol. Diagn. 4:353 [1999].
Ryan et al., Mol. Diagn. 4:135 [1999].
Ma et al., J. Biol. Chem., 275:24693 [2000].
Reynaldo et al., J. Mol. Biol., 297:511 [2000].
Kaiser et al., J. Biol. Chem., 274:21387 [1999].

Affiliated with

Also associated with

Rating

Solid-phase reactions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Solid-phase reactions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Solid-phase reactions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3879870