Solid phase radioimmunoassay of digoxin

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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Details

23230B, 424 12, A61K 4300, G01T 116, G01T 1167, G21H 502

Patent

active

039339971

ABSTRACT:
Clinically significant concentrations of digoxin can be determined by reacting an unknown amount of digoxin, a known amount of labelled digoxin, and a composite consisting of anti-digoxin antibodies coupled through an intermediate silane to magnetically responsive particles; magnetically separating the immunochemical complexes formed thereby, counting the radioactivity of either the separated products or remaining solution, and relating the count to a standard curve.

REFERENCES:
patent: 3519538 (1970-07-01), Messing et al.
patent: 3652761 (1972-03-01), Weetall

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