Chemical apparatus and process disinfecting – deodorizing – preser – Chemical reactor – Organic polymerization
Patent
1997-07-25
1998-08-11
Bhat, Nina
Chemical apparatus and process disinfecting, deodorizing, preser
Chemical reactor
Organic polymerization
422102, 422103, 422116, 422134, 422138, 536 231, C08F25100, B01J 1900
Patent
active
057924309
ABSTRACT:
A solid phase organic synthesis device comprising a manifold and an optional heating block mounted to an upper surface of the manifold. The manifold includes an internal cavity and a first array of holes coupled to the internal cavity. The heating block includes a second array of holes vertically aligned with the corresponding holes of the first array. The first and second arrays of holes are adapted to accommodate flow-through reaction vessels. Each reaction vessel is secured in one of the holes of the first array and a vertically-aligned one of the holes of the second array. The interiors of the reaction vessels are in communication with the internal cavity of the manifold. The flow-through reaction vessels, which contain solid phase resins for solid phase organic synthesis, are controlled by regulating the pressure within the manifold. The manifold includes a pressure port coupled to both an inert gas source and a pressure control device, and a vacuum port coupled to a vacuum control device and a vacuum source. The pressure control device and the vacuum control device are easily operated to create a vacuum and varying degrees of positive pressure within the manifold, as required when carrying out an organic synthesis. A second manifold is mounted on the first manifold in the absence of the reaction vessels for supplying inert gas used to concentrate organic synthesis products.
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Bhat Nina
Bonner Grace L.
Monsanto Company
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