Solid phase anti-C3 assay for detection of immune complexes

Chemistry: physical processes – Physical processes – Crystallization

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422 57, 422 61, 424 1, 424 12, 435 7, G01N 3354, G01N 3356

Patent

active

043425666

ABSTRACT:
A solid phase assay which specifically detects C-fixing ICs by reacting ICs or aggregated gammaglobulin in normal serum with matrix-bound F(ab')2 anti-C3 and measuring the amount of Ig by radioimmunoassay or enzyme-linking techniques, and means for carrying out the assay are disclosed.

REFERENCES:
patent: 4138213 (1979-02-01), Masson
patent: 4141965 (1979-02-01), Soothill
patent: 4153417 (1979-05-01), Hallgren
patent: 4162895 (1979-07-01), Camblaso
patent: 4169138 (1979-09-01), Jonsson
patent: 4184847 (1980-01-01), Hallgren
patent: 4200436 (1980-04-01), Mochida
patent: 4210622 (1980-07-01), Soothill
"Manual of Clinical Immunology," Noel R. Rose et al., eds. Chapt. 91, American Society for Microbiology, Washington, D.C., 1976.

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