Solid pharmaceutical sustained-release form

Details Solid pharmaceutical sustained-release form Solid pharmaceutical sustained-release form

1989-10-24

1993-12-14

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424472, 424480, 424482, 424475, 424498, A61K 924, A61K 936, A61K 942

Patent

active

052700550

ABSTRACT:
A solid pharmaceutical sustained-release form, consisting of a core containing the active compound as well as conventional pharmaceutical auxiliaries, a coat which delays the release of the active compound and an antiadhesive outer layer, wherein the coat consists of a physiologically acceptable fat-like or wax-like hydrophobic layer which melts in the range from 30.degree. to 120.degree. C. and contains, in addition to conventional pharmaceutical auxiliaries, one or more water-insoluble polymers, and a process for its preparation.

REFERENCES:
patent: 3939259 (1976-02-01), Pescetti
patent: 4289795 (1981-09-01), Bogentoft et al.
patent: 4716041 (1987-12-01), Kjornaes et al.
patent: 4723034 (1988-02-01), Schimer et al.
patent: 4755387 (1988-07-01), Tzeghai et al.
patent: 4822908 (1989-04-01), Karbach et al.
Patent Abstracts of Japan, No. 178, Aug. 1984, Sankyo K.K. (The Patent Office Japanese Government).
Patent Abstracts of Japan, No. 138, Nov. 1979, Nippon Kayaku K.K. The Patent Office of Japanese Government.

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