Solid pharmaceutical or diagnostic agent containing dextran and

Details Solid pharmaceutical or diagnostic agent containing dextran and Solid pharmaceutical or diagnostic agent containing dextran and

1980-05-30

1982-02-09

Rosen, Sam

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424 94, 424227, 424271, 424330, 435183, 435188, 435191, 435215, 435216, 435217, 435219, A61K 3171, A61K 3748, C12N 900

Patent

active

043150020

ABSTRACT:
A process for the preparation of a solid pharmaceutical or diagnostic composition in which the active substance and dextran are dissolved in water, the solution is placed in a mold and is thereafter lyophilized to form a solid abrasion-resistant tablet which can further be compressed to reduce its rate of disintegration in water. The invention is also directed to the pharmaceutical or diagnostic agent produced by this process.

REFERENCES:
patent: 3655838 (1972-04-01), Price et al.
patent: 4134943 (1979-01-01), Knitsch et al.
Kengo-Chem. Abst., vol. 87 (1977), p. 65,650r.
Briggs et al.-Chem. Abst., vol. 76 (1972), p. 131,492d.
Murakami et al.-Chem. Abst., vol. 83, (1975), p. 136,908y.
Okazaki et al.-Chem. Abst., vol. 87, (1977), p. 106,748m.
Okazaki et al.-Chem. Abst., vol. 86, (1977), p. 127,281y.

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