Solid pharmaceutical formulations for slow, zero order release v

Details Solid pharmaceutical formulations for slow, zero order release v Solid pharmaceutical formulations for slow, zero order release v

1983-07-07

1985-09-03

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 22, 424 32, 424 35, 514161, 514960, A61K 922, A61K 932, A61K 936, A61K 3160

Patent

active

045391980

ABSTRACT:
A new class of solid pharmaceutical formulations enables the attainment of slow, zero order in vivo release of a wide range of pharmaceutically active ingredients upon oral administration. A broad range of release rates can be preselected by suitable adjustments of tablet properties. The formulations are based upon control of active ingredient release from the surface of the tablet via a controlled surface erosion mechanism. These compositions comprise:

REFERENCES:
patent: 4264573 (1981-04-01), Powell et al.
patent: 4361545 (1982-11-01), Powell et al.
Porter et al., "The Permeability of Enteric Coatings and the Dissolution Rates of Coated Tablets", Jun. 5, 1981, pp. 5-8.
Remington's Pharmaceutical Sciences, 1970, pp. 1689-1691.
Porter, "Tablet Coating," Jun. 1981, pp. 44, 46, 48, 50, 51, 86, 90, 92, 94.
Luce, "Cellulose Acetate Phthalate: A Versatile Enteric Coating", Jun. 1977.
Rasmussen, "5-Aminosalicylic Acid in a Slow-Release Preparation: Bioavailability, Plasma Level, and Excretion in Humans," 1982, pp. 1062-1070.

Affiliated with

Also associated with

Rating

Solid pharmaceutical formulations for slow, zero order release v does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Solid pharmaceutical formulations for slow, zero order release v, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Solid pharmaceutical formulations for slow, zero order release v will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-613105