Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Reexamination Certificate
2006-01-10
2006-01-10
Page, Thurman K. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
C424S464000, C424S465000, C424S451000, C424S452000, C424S489000
Reexamination Certificate
active
06984399
ABSTRACT:
The present invention relates to a novel solid pharmaceutical formulation containing lovastatin and simvastatin, respectively, with a particle size D(0.9) between 15 and 100 μm and a specific particle surface area between 1 and 4 m2/g, and to the process for its preparation. The present invention also relates to the method for production of lovastatin and simvastatin with the size of crystals which are suitable for the preparation of the pharmaceutical formulation of the present invention. The novel solid pharmaceutical formulation is useful for treating hypercholesterolemia and hyperlipidemia.
REFERENCES:
patent: 5314506 (1994-05-01), Midler, Jr. et al.
patent: 6235311 (2001-05-01), Ullah et al.
patent: 6696086 (2004-02-01), Pflaum et al.
Lennernas, Hans, et al. “Pharmacodynamics and Pharmacokinetics of the HMG-CoA Reductase Inhibitors,” pp. 403-425, May 1997.
Pavia, D., et al., “Introduction to Organic Laboratory Techniques—A Contemporary Approach,” 2ndEdition, pp. 488-490, 1982.
Zubrick, James W. “The Organic Chem Lab Survival Manual—A Student's Guide to Techniques,”John Wiley&Sons, pp 102-107, 1988.
Jerala Zdenka
Pflaum Zlatko
Resman Aleksander
Salobir Mateja
Bromberg & Sunstein LLP
Lek Pharmaceuticals d.d.
Page Thurman K.
Sheikh Humera N.
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