Solid microparticles for gene delivery

Details Solid microparticles for gene delivery Solid microparticles for gene delivery

1996-06-07

2000-02-15

Stanton, Brian R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

4353201, 435440, 435455, C12N 1500, A01N 4304

Patent

active

060253371

ABSTRACT:
A target-specific gene delivery system is made of enzymatically degradable gelatin and nucleic acids (DNA or RNA) microparticles with a linking moiety or a targeting ligand attached to the surface. The delivery system can be made by a simple method. Targeting ligands can be attached to the microparticle directly or via a linking moiety. The linkage design allows the attachment of any molecule onto the microparticle surface including antibodies, cell adhesion molecules, hormones and other cell-specific ligands.

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