Solid matrix system for transdermal drug delivery

Details Solid matrix system for transdermal drug delivery Solid matrix system for transdermal drug delivery

1994-09-26

1998-06-23

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424448, A61F 1302

Patent

active

057702195

ABSTRACT:
A matrix for containing drugs for transdermal delivery systems is disclosed. The matrix, formed of a skin-adhesive acrylate copolymer, attains high rates of drug delivery without the addition of drug delivery rate enhancers. In preferred embodiments the matrix is used to administer steroids, in particular estradiol. Water-soluble polymers may be added as well.

REFERENCES:
patent: 3426754 (1969-02-01), Bierenbaum et al.
patent: 3632740 (1972-01-01), Robinson et al.
patent: 3645835 (1972-02-01), Hodgson
patent: 3685734 (1972-08-01), Paciorek et al.
patent: 3725122 (1973-04-01), Reinhard et al.
patent: 3769071 (1973-10-01), Trancik
patent: 3849238 (1974-11-01), Gould et al.
patent: 3896789 (1975-07-01), Trancik
patent: 4181752 (1980-01-01), Martens et al.
patent: 4331651 (1982-05-01), Reul et al.
patent: 4379454 (1983-04-01), Campbell et al.
patent: 4421737 (1983-12-01), Ito et al.
patent: 4438139 (1984-03-01), Keith et al.
patent: 4452845 (1984-06-01), Lloyd et al.
patent: 4460372 (1984-07-01), Campbell et al.
patent: 4510197 (1985-04-01), Shah
patent: 4552751 (1985-11-01), Inaba et al.
patent: 4560553 (1985-12-01), Zupan
patent: 4608249 (1986-08-01), Otsuka et al.
patent: 4655768 (1987-04-01), Marecki et al.
patent: 4668232 (1987-05-01), Cordes et al.
patent: 4687481 (1987-08-01), Nuwayser
patent: 4695465 (1987-09-01), Kigasawa et al.
patent: 4781926 (1988-11-01), Hyon et al.
patent: 4818540 (1989-04-01), Chien et al.
patent: 4883669 (1989-11-01), Chien et al.
patent: 4906169 (1990-03-01), Chien et al.
patent: 4906475 (1990-03-01), Kim
patent: 4971799 (1990-11-01), Nakagawa et al.
patent: 4994267 (1991-02-01), Sablotsky
patent: 5023084 (1991-06-01), Chien et al.
patent: 5059189 (1991-10-01), Cilento et al.
patent: 5069909 (1991-12-01), Sharma
patent: 5145682 (1992-09-01), Chien et al.
patent: 5152997 (1992-10-01), Ebert et al.
patent: 5223261 (1993-06-01), Nelson et al.
patent: 5252334 (1993-10-01), Chiang et al.
patent: 5296230 (1994-03-01), Chien et al.
patent: 5314694 (1994-05-01), Gale et al.
patent: 5362497 (1994-11-01), Yamada et al.
patent: 5376377 (1994-12-01), Gale et al.
patent: 5422119 (1995-06-01), Casper
patent: 5505956 (1996-04-01), Kim et al.
patent: 5554381 (1996-09-01), Roos et al.
patent: 5560922 (1996-10-01), Chien et al.
Translation of Japanese laid-open patent publ. No. 7-101853, laid-open publ. date Apr. 18, 1995.
Abstract of Japanese Patent No. 6-279266 from Derwent World Patent Index, Oct. 4, 1994.
Abstract of Japanese Patent No. 4-368322 from Derwent World Patent Index, Jun. 12, 1991.
Megrab et al. "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation" J. Controlled Release (1995) 36:277-294.
English Abstract of Japanese Laid-Open Patent Publication Number 57-075917. Laid-Open Publication Date: May 12, 1982.
English Abstract of Japanese Laid-Open Patent Publication Number 61-151122. Laid-Open Publication Date: Jul. 9, 1986.
Kligman et al., "Preparation of isolated sheets of human stratum corneum" Arch. Dermatol. (1963) 88:702-705.
Nitto Electric Industrial Co., Ltd., "Transdermal analgesic tapes" Chemical Abstracts (1985) 102:354 (Abstract 154817h).
Translation of Japanese Laid-Open Patent Publication Number 60-66759. Laid-Open Publication Date: Apr. 16, 1985.
Translation of Japanese Laid-Open Patent Publication Number 60-123417. Laid-Open Publication Date: Jul. 2, 1985.
Wolff, "In vitro models in the development of transdermal drug delivery systems and their practical relevance for in vivo transdermal absorption" Transdermal Drug Delivery Jaeger et al., eds., Neu-Ulm Conference (1986) pp. 68-76.

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