Solid forms of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S360000

Reexamination Certificate

active

08039473

ABSTRACT:
The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease.

REFERENCES:
patent: 2008/0214561 (2008-09-01), Bubendorf et al.
patent: 2004/071486 (2004-08-01), None
patent: 2004071486 (2004-08-01), None
patent: 2005/014563 (2005-02-01), None
Hancock et al. Pharm. Res. 17(4), pp. 397-404 (2000).
International Search Report issued Apr. 8, 2008 in corresponding PCT/EP2007/064104.
Translation of Chinese Office Action dated May 24, 2011.

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