Solid, fast-soluble pharmaceutical preparation containing S-(car

Details Solid, fast-soluble pharmaceutical preparation containing S-(car Solid, fast-soluble pharmaceutical preparation containing S-(car

1993-08-02

1995-03-28

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424440, 424441, 424464, 514781, 514784, A61K 920, A61K 31195

Patent

active

054015146

ABSTRACT:
The compact, solid drug preparation, which contains N-acetylcysteine and/or S-(carboxymethyl)-L-cysteine, is suitable, despite small amounts of inactive ingredients, both for swallowing and for sucking or dissolving in water or an aqueous solution. The compactness of the drug preparation is guaranteed by a high proportion of active ingredients--more than 50% of the total weight--and by a suitable choice of a tableting adjuvant.

REFERENCES:
patent: 4968506 (1990-11-01), Appelgren et al.
patent: 4970236 (1990-11-01), Ziggiotti et al.
"Acetylcysteine: A Drug with an Interesting Past and a Fascinating Future," Irwin Ziment, Respiration, 50: Suppl. 1, pp. 26-30 (1986).
"Acetylcysteine: A Drug That is Much More Than a Mucokinetic," I. Ziment, Biomed. & Pharmacother., 42:513-520 (1988).
"Acetylcystein," Information Und Beratung, p. 1873, Detusche Apotheker Zeitung, 130 Jargh, Nr. 34, 23.8 (1990).

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