Solid dosage form of wetted heparin

Details Solid dosage form of wetted heparin Solid dosage form of wetted heparin

2005-05-06

2011-10-18

Ward, Paul V. (Department: 1624)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C514S093000, C585S001000

Reexamination Certificate

active

08039018

ABSTRACT:
The present invention relates to a solid pharmaceutical composition (such as a solid dosage form) comprising a delivery agent and wetted heparin. The inclusion of wetted heparin rather than un-wetted heparin in the solid pharmaceutical composition results in increased delivery of the heparin. Without being bound by any particular theory, applicants believe that because the polymer chain of the wetted heparin is already in an “open” form, while un-wetted heparin is not, less of the wetted heparin is broken down in the gastrointestinal tract and is more readily absorbed in the stomach.

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