Solid compositions containing polyethylene oxide and an active i

Details Solid compositions containing polyethylene oxide and an active i Solid compositions containing polyethylene oxide and an active i

1997-10-14

2000-09-12

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424465, 424464, 424469, 514960, 514961, A61K 920, A61K 914, A61K 926

Patent

active

06117453&

ABSTRACT:
A solid composition is disclosed comprising an active ingredient that is not in amorphous form in association with polyethylene oxide and conventional additives, excluding basic compounds. Such compositions are suitable for use as pharmaceutical compositions. A method for their preparation is also disclosed.

REFERENCES:
patent: 4404186 (1983-09-01), Kawata et al.
patent: 5037653 (1991-08-01), Dawson
patent: 5273758 (1993-12-01), Royce
patent: 5654004 (1997-08-01), Chen et al.
patent: 5766623 (1998-06-01), Ayres et al.
A. Apicella, B. Cappello, M.A. Del Nobile, M.I. La Rotonda, G. Mensitieri and L. Nicolais, "Poly[ethylene oxide][PEO]and different molecular weight PEO blends monolithic devices for drug release," Biomaterials, 1993, pp. 83-90.

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