Liquid purification or separation – With means to add treating material – Chromatography
Reexamination Certificate
2011-05-24
2011-05-24
Therkorn, Ernest G (Department: 1776)
Liquid purification or separation
With means to add treating material
Chromatography
C210S502100, C210S635000, C210S656000
Reexamination Certificate
active
07947174
ABSTRACT:
A method of preparing a sol-gel monolithic column includes the step of forming a separation bed (14) from a sol-gel solution in a single process step. This column has improved characteristics for CEC based on its incorporated surface charge and ease of operation due to a lack of or need for end frits. Also, a second type of column includes an optical window (30) for on-column detection.
REFERENCES:
patent: 4509964 (1985-04-01), Hubball et al.
patent: 4675300 (1987-06-01), Zare et al.
patent: 4966785 (1990-10-01), Springston
patent: 5128291 (1992-07-01), Wax et al.
patent: 5192406 (1993-03-01), Woolley
patent: 5240577 (1993-08-01), Jorgenson et al.
patent: 5262052 (1993-11-01), Rossiter et al.
patent: 5270027 (1993-12-01), Balducci et al.
patent: 5308495 (1994-05-01), Avnir et al.
patent: 5522994 (1996-06-01), Frechet et al.
patent: 5589396 (1996-12-01), Frye et al.
patent: 5624875 (1997-04-01), Nakanishi et al.
patent: 5637135 (1997-06-01), Ottenstein et al.
patent: 5691206 (1997-11-01), Pawliszyn
patent: 5869152 (1999-02-01), Colon
patent: 6136187 (2000-10-01), Zare et al.
patent: 6344242 (2002-02-01), Stolk et al.
patent: 6613234 (2003-09-01), Voute et al.
patent: 6759126 (2004-07-01), Malik et al.
patent: 6783680 (2004-08-01), Malik
patent: 6998040 (2006-02-01), Malik et al.
patent: 2003/0075447 (2003-04-01), Malik et al.
patent: 2004/0129141 (2004-07-01), Malik et al.
patent: 2005/0106068 (2005-05-01), Malik et al.
patent: 2006/0013981 (2006-01-01), Malik et al.
patent: 2006/0013982 (2006-01-01), Malik et al.
patent: 2006/0113231 (2006-06-01), Malik
patent: 2007/0062874 (2007-03-01), Malik et al.
patent: 2007/0095736 (2007-05-01), Malik et al.
patent: 2007/0172960 (2007-07-01), Malik et al.
patent: WO-00-11463 (2000-03-01), None
patent: WO 00/11463 (2000-03-01), None
patent: WO-02-072225 (2002-09-01), None
patent: WO-02-094410 (2002-11-01), None
Merriam-Webster's Collegiate Dictionary, Tenth Edition, Merriam-Webster, Incorporated, Springfield Massachusetts 1998, p. 555.
Zhang (Journal of Liquid Chromatography, 18(17), 3373-3396 (1995).
Behnke et al., “Pressurized gradient electro-high-performance liquid chromatography,” J. Chromatogr. A. 680:93-98, 1994.
Behnke et al., “Evaluation of the parameters determining the performance of electrochromatography in packed capillary columns,” J. Chromatogr. A. 716:207-213, 1995.
Colon et al., “Ninth International Symposium on High Performance Capillary Electrophoresis and Related Microscale Techniques,” (HPCE '97). Anaheim, California 1997. Abstract.
Dittmann et al., “Capillary electrochromatography—a high-efficiency micro-separation technique,” J. Chromatogr. A. 744:63-74, 1996.
Dulay et al., “Automated capillary electrochromatography: reliability and reproducibility studies,” J. Chromatogr. A. 725:361-366, 1996.
Ericson et al., “Preparation of continuous beds for electrochromatography and reversed-phase liquid chromatography of low-molecular-mass compounds,” J. Chromatogr. A. 767:33-41, 1997.
Ericson et al., “Reversed-Phase Electrochromatography of Proteins on Modified Continuous Beds Using Normal-Flow and Counterflow Gradients. Theoretical and Practical Considerations,” Anal. Chem. 71:1621-1627, 1999.
Frame et al., “Simplification of capillary electrochromatography procedure's,” J. Chromatogr. A. 798:243-249, 1998.
Fujimoto et al., “Charged Polyacrylamide Gels for Capillary Electrochromatographic Separations of Uncharged, Low Molecular Weight Compounds,” Anal. Chem. 67:2050-2053, 1995.
Fujimoto et al., “Fritless Packed Columns for Capillary Electrochromatography: Separation of Uncharged Compounds on Hydrophobic Hydrogels,” Anal. Chem. 68:2753-2757, 1996.
Hayes et al., “Sol-Gel Monolithic Columns with Reversed Electroosmotic Flow for Capillary Electrochromatography,” Anal. Chem. 72:4090-4099, 2000.
Hileman et al., “In Situ Preparation and Evaluation of Open Pore Polyurethane Chromatographic Columns,” Anal. Chem. 45:1126-1130, 1973.
Hjerten et al., “High-performance liquid chromatography on continuous polymer beds,” J. Chromatogr. 473:273-275, 1989.
Hjerten et al., “Continuous beds: high-resolving, cost-effective chromatographic matrices,” Nature 356:810-811, 1992.
Ishizuka et al., “Designing monolithic double-pore silica for high-speed liquid chromatography,” J. Chromatogr. A. 797:133-137, 1998.
Jorgenson et al., “High-Resolution Separations Based on Electrophoresis and Electroosmosis.” J. Chromatogr. A. 218:209-216, 1981.
Knox et al., “Miniaturisation in Pressure and Electroendosmotically Driven Liquid Chromatography: Some Theoretical Considerations,” Chromatographia 24:135-143, 1987.
Li et al., “Continuous Beds for Microchromatography: Cation-Exchange Chromatography,” Anal. Biochem. 223:153-158, 1994.
Ludtke et al., “Application of 0.5-μm porous silanized silica beads in electrochromatography,” J. Chromatogr. A. 786:229-235, 1997.
Minakuchi et al., “Effect of domain size on the performance of octadecylsilylated continuous porous silica columns in reversed-phase liquid chromatography,” J. Chromatogr. A. 797:121-131, 1998.
Moffatt et al., “Capillary Electrochromatography. Abnormally High Efficiencies for Neutral-Anionic Compounds under Reversed-Phase Conditions,” Anal. Chem. 71:1119-1124, 1999.
Nakanishi et al., “Double Pore Silica Gel Monolith Applied to Liquid Chromatography,” J. Sol-Gel Sci. and Tech. 8:547-558, 1997.
Palm et al., “Macroporous Polyacrylamide/Poly(ethylene glycol) Matrixes as Stationary Phases in Capillary Electrochromatography,” Anal. Chem. 69:4499-4507, 1997.
Peters et al., “Molded Rigid Polymer Monoliths as Separation Media for Capillary Electrochromatography,” Anal. Chem. 69:3646-3649, 1997.
Peters et al., “Molded Rigid Polymer Monoliths as Separation Media for Capillary Electrochromatography. 1. Fine Control of Porous Properties and Surface Chemistry.” Anal. Chem. 70:2288-2295, 1998.
Pietrzyk et al., “Ion Exchangers,” Packings and Stationary Phases in Chromatographic Techniques; Unger, K.K., vol. 47, Marcel Dekker, Inc.: New York and Basel, 1990, Chapter 10.
Pretorius et al., “Electro-Osmosis a New Concept for High-Speed Liquid Chromatography,” J. Chromatogr. 99:23-30, 1974.
Seifar et al., “Capillary electrochromatography with 1.8-μm ODS-modified porous silica particles,” J. Chromatogr. A. 808:71-77, 1998.
Smith et al., “Capillary zone electrophoresis in pharmaceutical and biomedical analysis,” Journal of Pharmaceutical & Biomedical Analysis 12:579-611, 1994.
Svec et al., “Continuous Rods of Macroporous Polymer as High-Performance Liquid Chromatography Separation Media,” Anal. Chem. 64:820-822, 1992.
Svec et al.,“Modified poly(glycidyl methacrylate-co-ethylene dimethacrylate) continuous rod columns for preparative-scale ion-exchange chromatography of proteins,” J. Chromatogr. A. 702:89-95, 1995.
Tang et al., “Continuous Bed Columns Containing Sol-Gel Bonded Large-Pore Octadecylsilida for Capillary Electrochromatography,” J. Microcol. Sep. 11:550-561, 1999.
Tsuda, T., “Electrochromatography Using High Applied Voltage,” Anal. Chem. 59:521-523, 1987.
Van Den Bosch, “Experiences with packed capillary electrochromatography at ambient pressure,” J. Chromatogr. A. 755:165-177, 1996.
Wang et al., “Macroporous Polymeric Stationary-Phase Rod as Continuous Separation Medium for Reversed-Phase Chromatography,” Anal. Chem. 65:2243-2248, 1993.
Brinker, C.J.; Scherer, G.W.,Sol-gel Science: The Physics and Chemistry of Sol-gel Processing, Academic Press, San Diego, CA 1990.
Chong, S.; Wang, D.; Hayes, J.D.; Wilhite, B.W.; Malik, A.,Sol-Gel Coating Technology for the Preparation of Solid-Phase Microextraction Fibers of En
Hayes James D.
Malik Abdul
Saliwanchik Lloyd & Eisenschenk
Therkorn Ernest G
University of South Florida
LandOfFree
Sol-gel monolithic column with optical window and method of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sol-gel monolithic column with optical window and method of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sol-gel monolithic column with optical window and method of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2642060