Soft contact lens wetting solution and in-eye comfort solution c

Details Soft contact lens wetting solution and in-eye comfort solution c Soft contact lens wetting solution and in-eye comfort solution c

1984-08-20

1985-12-24

Willis, Prince E.

Compositions

Compositions containing a single chemical reactant or plural...

Organic reactant

252173, 25217423, 25217424, 252351, 252DIG2, 252DIG14, 422 28, C11D 348

Patent

active

045604916

ABSTRACT:
Aqueous compositions for the wetting and rewetting of contact lenses and especially silicone, silicone copolymer (gas-permeable) and soft contact lenses are provided that include a preservative system. The preservative system includes trimethoprim, and benzyl alcohol as an adjuvant bactericide and optionally a salt of EDTA. The use of preservatives which are known to cause eye irritation and lens discoloration such as thimerosal, sorbic acid, potassium chloride and chlorhexidine is eliminated. Wetting and re-wetting compositions which incorporate the preservative system and include thickening and wetting agents are also provided. The wetting and re-wetting solutions can be instilled directly into the eye during contact lens wearing periods and are especially useful for wetting silicone, silicone copolymer and soft daily and extended wear contact lenses.

REFERENCES:
patent: 3549747 (1970-12-01), Krezanoski et al.
patent: 3639576 (1972-02-01), Kaspar et al.
patent: 3954965 (1976-05-01), Boghosian et al.
patent: 4287175 (1981-09-01), Katz
patent: 4470978 (1984-09-01), Stolar
The Merck Index, An Encyclopedia of Chemicals & Drugs, Merck & Co., N.J. Ninth Ed., 1976, p. 1246

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