Soft capsules containing dinreburnamenine compounds

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424456, A61K 948

Patent

active

057076510

ABSTRACT:
A soft capsule containing a) a capsule casing containing gelatin and optionally a plasticizer and other additives, b) a compound of the formula ##STR1## wherein R1, R2 and R3 are individually selected from the group consisting of hydrogen, halogen, alkyl and alkoxy of 1 to 5 carbon atoms, --OH, --CF3, --NO2, --NH2, alkylamino and dialkylamino of 1 to 5 alkyl carbon atoms and acylamino of acyl of an aliphatic carboxylic acid of 1 to 6 carbon atoms or a non-toxic, pharmaceutically acceptable acid addition salt thereof and c) at least one mineral oil and optionally a pharmaceutical carrier.

REFERENCES:
patent: 4486412 (1984-12-01), Shah et al.
patent: 5093337 (1992-03-01), Aktogu et al.
patent: 5178877 (1993-01-01), Garren et al.
patent: 5324280 (1994-06-01), Wong et al.
patent: 5332748 (1994-07-01), Aktogu et al.
patent: 5413572 (1995-05-01), Wong et al.

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