Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1983-10-07
1986-02-25
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 22, 424 81, 514773, 514774, 514775, A61K 920, A61K 922, A61K 4700
Patent
active
045728321
ABSTRACT:
A soft buccal containing (1) a medicament to be absorbed through the oral mucosa, (2) a water-soluble protein, (3) a polyhydric alcohol, and (4) a fatty acid ester or/and a carboxyvinyl polymer, has various advantages such as good feeling in use, good retainability within the mouth, slow release, improved absorbability of drug through the mucosa, improved bioavailability, etc., and therefore can be used an excellent pharmaceutical preparation for administration to the mucous membrane of the mouth.
REFERENCES:
patent: 4059686 (1977-11-01), Tanaka et al.
patent: 4250163 (1981-02-01), Nagai et al.
patent: 4344968 (1982-08-01), Aoada et al.
Cyr C.A. 66, #118846w, (1967), of U.S. Pat. No. 3,312,594, 4/4/67.
Christenson et al., C.A. 75, #101284z, (1971) of U.S. Pat. No. 3,594,467, Jul. 20, 1971.
Teijin C.A. 94, #52962a, 59963b of JPN. 80118413 & 80118414, Sep. 11, 1980.
Hayashi Toshihiro
Kigasawa Kazuo
Koyama Osamu
Ogawa Yasuaki
Shimizu Hiroaki
Grelan Pharmaceutical Co. Ltd.
Rose Shep K.
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