Sodium N-acetylneuraminate trihydrate

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 111, 536127, 422 40, C07H 506, C07H 1302, A61K 3170

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active

052311775

ABSTRACT:
Sodium N-acetylneuraminate trihydrate herein provided is represented by the following formula: ##STR1## The sodium N-acetylneuraminate trihydrate can be prepared, for instance, according to a method which comprises the steps of: dissolving sodium N-acetylneuraminate in water or in a mixture of water and an organic solvent; allowing the resulting solution to stand; precipitating and separating the resulting crystals of sodium N-acetylneuraminate.trihydrate; and then drying the separated crystals. The sodium N-acetylneuraminate trihydrate has very low hygroscopicity and hence can be handled without any difficulty in the form of powder.

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H. Rinderknecht et al. "Synthesis of N-acetylneuraminic acid" Column 6497b.
Chemical Abstracts, vol. 52, No. 3, Feb. 10, 1958, Columbus, Ohio, USA.
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Chemical Abstracts, vol. 51, No. 18, Sep. 25, 1957, Columbus, Ohio, USA.
Cornforth et al. "Synthesis of N-acetylneuraminic acid (lactaminic acid), O-sialic acid)" Column 13858f.

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