Sodium enalapril complex and the use thereof to make sodium enal

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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5483341, 548402, C07D20709

Patent

active

056377304

ABSTRACT:
A process for making pure sodium enalapril is provided which includes the step of decomplexing essentially pure sodium enalapril-sodium iodide complex to yield essentially pure sodium enalapril.

REFERENCES:
patent: 4374829 (1983-02-01), Harris et al.
Med. Chem. Rev., 1985, 5, 483.
Adv. Drug Delivery Rev., 1992, 8, 253.
Drug Met. Dispos., 1982, 10, 15.
J. Pharm. Exp. Ther., 1981, 216, 552.
J. Pharm. Exp. Ther., 1983, 226, 192.

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