Sodium dihydrogen phosphate enhanced dentifrice composition

Details Sodium dihydrogen phosphate enhanced dentifrice composition Sodium dihydrogen phosphate enhanced dentifrice composition

1979-02-12

1980-04-15

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Fluorine or fluorine compound containing

424 57, A61K 718

Patent

active

041983947

ABSTRACT:
A sodium dihydrogen phosphate stannous fluoride containing dentifrice composition wherein the enamel penetration and effectiveness of the fluoride is enhanced by sodium dihydrogen phosphate causing the enamel crystalline latticework of the teeth to become activated and allowing the stannous fluoride to penetrate and remain in the tooth enamel for a sufficient period of time to render the enamel effectively resistant to the development of dental caries. The dentifrice also may include a carrier incorporating quantities of abrasive material for polishing, a sweetening agent, a flavoring agent and a foaming agent. Within the acid pH range of between 2 and 5 and preferably 3.5, the sodium dihydrogen phosphate compound alters the crystalline latticework of the enamel thus rendering it capable of inducing deep penetration of fluoride ions and, subsequent to fluoride penetration, a surface capping effect or sealing effect is developed by the stannous fluoride phosphate complex that is effectively resistant to the natural leaching effect of the oral fluids.

REFERENCES:
patent: 1471987 (1926-10-01), Vogt
patent: 1691504 (1928-11-01), Vogt
patent: 2069157 (1937-01-01), Sahyun
patent: 2876166 (1959-03-01), Nebergall
patent: 2876167 (1959-03-01), Manahan
patent: 3105013 (1963-09-01), Saul et al.
patent: 3282792 (1966-11-01), Fiscella
patent: 3462366 (1969-08-01), Luoma

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