Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2007-02-27
2007-02-27
O'Sullivan, Peter (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C514S652000, C564S325000, C564S330000, C564S335000, C564S353000, C564S354000
Reexamination Certificate
active
10824738
ABSTRACT:
The invention provides sodium channel modulating compounds of formula I:wherein X, Y, Q, R1, w, and R2have any of the values defined in the specification, and salts thereof, which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of formula (I) or a salt thereof, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).
REFERENCES:
patent: 3197434 (1965-07-01), Preston et al.
patent: 3247199 (1966-04-01), Marxer et al.
patent: 3340146 (1967-09-01), Werner
patent: 3449418 (1969-06-01), Werner
patent: 3598866 (1971-08-01), Nowak et al.
patent: 4008265 (1977-02-01), Suzuki et al.
patent: 5736568 (1998-04-01), Rafferty et al.
patent: 613 143 (1962-07-01), None
patent: 1219039 (1966-06-01), None
patent: 1584428 (1981-02-01), None
patent: 6600012 (1966-07-01), None
Lowe et al., Chem. Abst. 46:48437 (1952).
Benoit et al., Chem. Abst. 47:12092 (1953).
Ando et al., “Aromatic polyether polyureas”, Chemical Abstract Services, Accession No. 67:117575, XP002190008 (1963).
Ando et al., “Synthesis of polyamides by cyanoethylation of bisphenols. IX. Properties of some polyamides with p-phenyleneoxy groups in the chain”, Chemical Abstract Services, Accession No. 67:22785, XP002190009 (1966).
Carissimi et al., “Preparation and pharmacology of ethylalkylamine ethers derived from hydroxy and dihydroxydiphenyl sulfones and their quaternary salts”, Chemical Abstract Services, Accession No. CA53:8142c, XP002190011 (1954).
Gilbert et al., “Study of the effects of basic di- and tri-phenyl derivatives on malignant cell proliferations: an example of the application of correspondence factor analysis to structure-activity relationships (SAR)”, Chemical Abstract Services, Accession No. 122:23229, XP002190010 (1994).
Chinn Jason P.
Choi Seok-Ki
Fatheree Paul R.
Marquess Daniel
Turner S. Derek
Hagenah Jeffrey A.
O'Sullivan Peter
Theravance Inc.
LandOfFree
Sodium channel modulators does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sodium channel modulators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sodium channel modulators will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3864205