Snake venom lupus anticoagulant protein

Details Snake venom lupus anticoagulant protein Snake venom lupus anticoagulant protein

1995-10-31

1998-06-09

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 514822, 530326, 530350, A61K 3800, C07K 1700

Patent

active

057634033

ABSTRACT:
A lupus anticoagulant like protein obtained from Agkistrodon halys brevicaudus venom, methods and tests for detecting the presence of lupus anticoagulant in blood and methods of treating antiphospholipid syndrome and thrombotic disorders using the protein are disclosed.

REFERENCES:
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patent: 5453370 (1995-09-01), Triplett et al.
Fujimura et al, Biochemistry, vol. 30, pp. 1957-1964, 1991.
Atoda et al, J. Biochem, vol. 118, pp. 965-973, 1995.
Atoda et al, J. Biol. Chem., vol. 266, pp. 14903-14911, 1991.
Usami et al, Proc. Natl. Acad. Sci, USA, vol. 90, pp. 928-932, Feb. 1993.
Stocker et al, Toxicon, vol. 32, No. 10, pp. 1227-1236, 1994.

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