Smooth muscle relaxant process employing 10-imidoylphenoxazines

Details Smooth muscle relaxant process employing 10-imidoylphenoxazines Smooth muscle relaxant process employing 10-imidoylphenoxazines

1976-03-26

1977-09-06

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424257, 42424856, 42424858, A61K 31535

Patent

active

040468917

ABSTRACT:
Novel 10-imidoylphenoxazines and 10-imidoylacridans are prepared by reacting a phenoxazine or acridan having optional substituents selected from the group consisting of trifluoromethyl, halogen, dihalogen, alkyl or alkoxy with an imidoyl halide prepared in situ from amides and lactams. Illustrative embodiments are 10-(5-methyl-1-pyrrolin-2-yl)phenoxazine and 9,9-dimethyl-10-(5-methyl-1-pyrrolin-2-yl)acridan. The imidoylphenoxazines and imidoylacridan products are generally useful as smooth muscle relaxants.

REFERENCES:
patent: 3719671 (1973-03-01), Wu et al.

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