Smooth muscle peristole inhibitor

Details Smooth muscle peristole inhibitor Smooth muscle peristole inhibitor

2011-08-02

2011-08-02

Lundgren, Jeffrey S (Department: 1629)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

Reexamination Certificate

active

07989503

ABSTRACT:
An emulsion comprising L-Menthol, a fat or oil and a surfactant wherein oil particles have an average diameter of 100 nm or less inhibits a content reduction attributed to, for example, evaporation of L-menthol, enhances a light transmission through liquid and is stable despite long-term storage. Thus, the emulsion can be appropriately used in the temporary inhibition of contraction of gastrointestinal tract for, for example, observation of gastrointestinal tract by an endoscope. This emulsion can be obtained by heating an oil-in-water type emulsion comprising L-menthol, a fat or oil and a surfactant at 60° C. or higher.

REFERENCES:
patent: 3607651 (1971-09-01), Moroe et al.
patent: 4816247 (1989-03-01), Desai et al.
patent: 5364632 (1994-11-01), Benita et al.
patent: 5559157 (1996-09-01), Kawashima et al.
patent: 5925365 (1999-07-01), Yamamoto
patent: 6126954 (2000-10-01), Tsaur
patent: 2002/0012680 (2002-01-01), Patel et al.
patent: 2002/0068092 (2002-06-01), Bosch et al.
patent: 2003/0095990 (2003-05-01), Hua et al.
patent: 2003/0147927 (2003-08-01), Khan et al.
patent: 63-198634 (1988-08-01), None
patent: WO 00/42983 (2000-07-01), None
Nair, B: Final report on the safety assessment of mentha piperita (peppermint) oil, mentha piperita (peppermint) leaf extract, mentha peperita (peppermint) leaf, and mentha piperita (peppermint) leaf water. Int J Toxicol, 20 (suppl.3):61-73. 2001.
Ros: Intestinal absorption of triglyceride and cholesterol. Dietary and pharmacological inhibition to reduce cardiovascular risk. atherosclerosis, 151:357-379, 2000.
http://www.theherbarie.com/files/resource-center/formulating/Required—HLB—for—Oils—and—Lipids.pdf.
J.M. Hills et al., The Mechanism of Action of Peppermint Oil on Gastrointestinal Smooth Muscle, Gastroenterology, 1991, vol. 101, No. 1, pp. 55-65.
T. Asao et al., “An easy method for the intraluminal administration of peppermint oil before colonoscopy and its effectiveness in reducing colonic spasm”, Gastrointestinal Endoscopy, 2001, vol. 53, No. 2, pp. 172-177.

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