Smoking substitutes for nasal administration-I

Details Smoking substitutes for nasal administration-I Smoking substitutes for nasal administration-I

1984-01-11

1986-04-01

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

131270, 131347, 131352, 131359, A61K 31465

Patent

active

045798583

ABSTRACT:
A smoking substitute composition for application directly into the nose, consisting essentially of an aqueous solution of nicotine or a physiologically acceptable acid addition salt thereof, having a pH value of 2 to 6, containing 10 to 0.5% w/v of nicotine calculated as the free base, containing a nasally-acceptable thickening agent, and having a viscosity not less than 100 centipoise and optionally containing also a further ingredient selected from the group consisting of a nasally acceptable buffer, emulsifying agent, preservative, flavoring agent and antioxidant. A method of diminishing the desire of a subject to smoke comprising the step of administering to the subject a smoking substitute composition as set forth in the foregoing.

REFERENCES:
patent: 865026 (1907-09-01), Ellis
patent: 2346362 (1944-04-01), Dolman
patent: 2836329 (1958-05-01), Chenette
patent: 3069314 (1962-12-01), Jenkins
patent: 3170462 (1965-02-01), Hall
patent: 3171446 (1965-03-01), Koch
patent: 3252802 (1966-05-01), Cunningham
patent: 3368567 (1968-02-01), Speer
patent: 3870794 (1975-03-01), Hutchinson et al.
patent: 4117850 (1978-10-01), Wood
patent: 4284649 (1981-08-01), Wiczer

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