SMMR (small molecule metabolite reporters) for use as in...

Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-o

Reexamination Certificate

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C436S172000, C436S164000, C436S518000, C436S546000, C424S009600, C424S009100

Reexamination Certificate

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08008088

ABSTRACT:
Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

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