Smilagenin and its use

Details Smilagenin and its use Smilagenin and its use

2008-05-06

2008-05-06

Hoffman, Susan C (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

C514S026000

Reexamination Certificate

active

11621557

ABSTRACT:
The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.

REFERENCES:
patent: 3890438 (1975-06-01), Cayen et al.
patent: 4680289 (1987-07-01), Applezweig
patent: 4800080 (1989-01-01), Grollier et al.
patent: 5017562 (1991-05-01), Holmes et al.
patent: 5589182 (1996-12-01), Tashiro et al.
patent: 6258386 (2001-07-01), Xia et al.
patent: 6593301 (2003-07-01), Ma et al.
patent: 6812213 (2004-11-01), Xia et al.
patent: 1096031 (1994-12-01), None
patent: 4303214 (1994-08-01), None
patent: 1024146 (2000-08-01), None
patent: 9916786 (1999-08-01), None
Eberling et al. Experimental Neurology (2002). vol. 178, pp. 236-242.
Emborg; Journal of Neuroscience Methods (2004), vol. 139, pp. 121-143.
Martin, et al., Definition of “Alzheimer's disease,” The Bantam Medical Dictionary, 2nd Edition, 1981, p. 15, Bantam Books, New York.
Schwartz, Rochelle et al., “Presynaptic Nicotinic Cholinergic Receptors Labeled by [3H] Acetylcholine on Catecholamine and Serotonin Axons in Brain,” Journal of Neurochemistry, 1984, pp. 1495-1498, vol. 42, No. 5, Raven Press, New York.
Sramek, John J., et al., “A Bridging Study of LU-25-109 in Patients with Probable Alzheimer's Disease,” Life Sciences, 1998, pp. 195-202, vol. 62, No. 3, Elsevier Science, Inc.
Yi, Ningyu, et al., “Extraction of .beta.-adnergic receptor-and M cholinergic receptor-regulating (.beta,5.beta.,25s)-spirostan-3-ol from Anemarrhena Asphodeloides Bunge,” 1999. XP-002/17141.
Ma, Beiping, et al., “The Use of Steroidal Saponin Compounds to Prevent Senility, and Novel Steroid Saponin Compounds,” 1999. CAPLUS Abstract of WO99/6786.
Blunden et al., “Steroidal Sapogenins from Leaves of Agaveae Species” (Abstract), Phytochemistry, 1978, 17(11), 1923-1926.
Ningyu, et al., “Sarsasapogenin: Mechanism in Treating Senile Dementia,” (Paper 62), Synthesis and Applications of Isotopically Labelled Compounds, 1997, pp. 315-320, John Wiley & Sons Ltd.
Ningyu et al., “The Mechanism of a Sapogenin From Anemarrhenae Asphodeloides Bge in the Treatment of Senile Dementia” (Abstract), Proceedings of the 6th International Symp. of the International Isotope Society, Philadelphia, 1997, p. 103.

Affiliated with

Also associated with

Rating

Smilagenin and its use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Smilagenin and its use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Smilagenin and its use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3950817