Electrolysis: processes – compositions used therein – and methods – Electrolytic analysis or testing – Involving enzyme or micro-organism
Reexamination Certificate
2009-09-29
2011-12-27
Noguerola, Alex (Department: 1759)
Electrolysis: processes, compositions used therein, and methods
Electrolytic analysis or testing
Involving enzyme or micro-organism
C204S403020, C204S403040
Reexamination Certificate
active
08083924
ABSTRACT:
A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry; and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.
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Colman Fredric C.
Feldman Benjamin J.
Funderburk Jeffery V.
Heller Adam
Heller Ephraim
Abbott Diabetes Care Inc.
Baba Edward J.
Bozicevic Field & Francis LLP
Davy Brian
Noguerola Alex
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