Electrolysis: processes – compositions used therein – and methods – Electrolytic analysis or testing – Of biological material
Reexamination Certificate
2011-03-22
2011-03-22
Noguerola, Alex (Department: 1759)
Electrolysis: processes, compositions used therein, and methods
Electrolytic analysis or testing
Of biological material
C204S403020, C204S403140, C422S051000
Reexamination Certificate
active
07909984
ABSTRACT:
A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In addition, a second electron transfer agent, such as an enzyme, can be added to facilitate the electrooxidation or electroreduction of the analyte. The redox mediator is typically a redox compound bound to a polymer. The preferred redox mediators are air-oxidizable.The amount of analyte can be determined by coulometry. One particular coulometric technique includes the measurement of the current between the working electrode and a counter or reference electrode at two or more times. The charge passed by this current to or from the analyte is correlated with the amount of analyte in the sample. Other electrochemical detection methods, such as amperometric, voltammetric, and potentiometric techniques, can also be used.The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is provided as a second electron transfer agent.
REFERENCES:
patent: 3260656 (1966-07-01), Ross, Jr.
patent: 3506544 (1970-04-01), Silverman et al.
patent: 3623960 (1971-11-01), Williams
patent: 3653841 (1972-04-01), Klein
patent: 3719564 (1973-03-01), Lilly, Jr. et al.
patent: 3776832 (1973-12-01), Oswin et al.
patent: 3837339 (1974-09-01), Aisenberg et al.
patent: 3926760 (1975-12-01), Allen et al.
patent: 3972320 (1976-08-01), Kalman
patent: 3979274 (1976-09-01), Newman
patent: 4008717 (1977-02-01), Kowarski
patent: 4016866 (1977-04-01), Lawton
patent: 4055175 (1977-10-01), Clemens et al.
patent: 4059406 (1977-11-01), Fleet
patent: 4076596 (1978-02-01), Connery et al.
patent: 4098574 (1978-07-01), Dappen
patent: 4100048 (1978-07-01), Pompei et al.
patent: 4120205 (1978-10-01), Ripphahn et al.
patent: 4133735 (1979-01-01), Afromowitz et al.
patent: 4151845 (1979-05-01), Clemens
patent: 4168205 (1979-09-01), Danninger et al.
patent: 4172770 (1979-10-01), Semersky et al.
patent: 4178916 (1979-12-01), McNamara
patent: 4206755 (1980-06-01), Klein
patent: 4210156 (1980-07-01), Bennett
patent: 4216245 (1980-08-01), Johnson
patent: 4224125 (1980-09-01), Nakamura et al.
patent: 4225410 (1980-09-01), Pace
patent: 4240438 (1980-12-01), Updike et al.
patent: 4240889 (1980-12-01), Yoda et al.
patent: 4247297 (1981-01-01), Berti et al.
patent: 4271119 (1981-06-01), Columbus
patent: 4318784 (1982-03-01), Higgins et al.
patent: 4339317 (1982-07-01), Meiattini et al.
patent: 4340458 (1982-07-01), Lerner et al.
patent: 4352960 (1982-10-01), Dormer et al.
patent: 4356074 (1982-10-01), Johnson
patent: 4365637 (1982-12-01), Johnson
patent: 4366033 (1982-12-01), Richter et al.
patent: 4375399 (1983-03-01), Havas et al.
patent: 4384586 (1983-05-01), Christiansen
patent: 4388166 (1983-06-01), Suzuki et al.
patent: 4390621 (1983-06-01), Bauer
patent: 4392933 (1983-07-01), Nakamura et al.
patent: 4401122 (1983-08-01), Clark, Jr.
patent: 4404066 (1983-09-01), Johnson
patent: 4407959 (1983-10-01), Tsuji et al.
patent: 4418148 (1983-11-01), Oberhardt
patent: 4420564 (1983-12-01), Tsuji et al.
patent: 4427770 (1984-01-01), Chen et al.
patent: 4431004 (1984-02-01), Bessman et al.
patent: 4436094 (1984-03-01), Cerami
patent: 4440175 (1984-04-01), Wilkins
patent: 4444892 (1984-04-01), Malmros
patent: 4450842 (1984-05-01), Zick et al.
patent: 4458686 (1984-07-01), Clark, Jr.
patent: 4461691 (1984-07-01), Frank
patent: 4462405 (1984-07-01), Ehrlich
patent: 4469110 (1984-09-01), Slama
patent: 4477314 (1984-10-01), Richter et al.
patent: 4483924 (1984-11-01), Tsuji et al.
patent: 4484987 (1984-11-01), Gough
patent: 4522690 (1985-06-01), Venkatasetty
patent: 4524114 (1985-06-01), Samuels et al.
patent: 4526661 (1985-07-01), Steckhan et al.
patent: 4534356 (1985-08-01), Papadakis
patent: 4538616 (1985-09-01), Rogoff
patent: 4543955 (1985-10-01), Schroeppel
patent: 4545382 (1985-10-01), Higgins et al.
patent: 4552840 (1985-11-01), Riffer
patent: 4560534 (1985-12-01), Kung et al.
patent: 4571292 (1986-02-01), Liu et al.
patent: 4573994 (1986-03-01), Fischell et al.
patent: 4581336 (1986-04-01), Malloy et al.
patent: 4595011 (1986-06-01), Phillips
patent: 4595479 (1986-06-01), Kimura et al.
patent: 4615340 (1986-10-01), Cronenberg et al.
patent: 4619754 (1986-10-01), Niki et al.
patent: 4627445 (1986-12-01), Garcia et al.
patent: 4627908 (1986-12-01), Miller
patent: 4629563 (1986-12-01), Wrasidlo
patent: 4633878 (1987-01-01), Bombardieri
patent: 4637403 (1987-01-01), Garcia et al.
patent: 4650547 (1987-03-01), Gough
patent: 4653513 (1987-03-01), Dombrowski
patent: 4654197 (1987-03-01), Lilja et al.
patent: 4655880 (1987-04-01), Liu
patent: 4655885 (1987-04-01), Hill et al.
patent: 4671288 (1987-06-01), Gough
patent: 4679562 (1987-07-01), Luksha
patent: 4680268 (1987-07-01), Clark, Jr.
patent: 4682602 (1987-07-01), Prohaska
patent: 4684537 (1987-08-01), Graetzel et al.
patent: 4685463 (1987-08-01), Williams
patent: 4703756 (1987-11-01), Gough et al.
patent: 4711245 (1987-12-01), Higgins et al.
patent: 4717673 (1988-01-01), Wrighton et al.
patent: 4721601 (1988-01-01), Wrighton et al.
patent: 4721677 (1988-01-01), Clark, Jr.
patent: 4726378 (1988-02-01), Kaplan
patent: 4726716 (1988-02-01), McGuire
patent: 4750496 (1988-06-01), Reinhart et al.
patent: 4757022 (1988-07-01), Shults et al.
patent: 4758323 (1988-07-01), Davis et al.
patent: 4759371 (1988-07-01), Franetzki
patent: 4759828 (1988-07-01), Young et al.
patent: 4764416 (1988-08-01), Ueyama et al.
patent: 4764485 (1988-08-01), Loughran et al.
patent: 4776944 (1988-10-01), Janata et al.
patent: 4781798 (1988-11-01), Gough
patent: 4784736 (1988-11-01), Lonsdale et al.
patent: 4787398 (1988-11-01), Garcia et al.
patent: 4795707 (1989-01-01), Niiyama et al.
patent: 4796634 (1989-01-01), Huntsman et al.
patent: 4805624 (1989-02-01), Yao et al.
patent: 4813424 (1989-03-01), Wilkins
patent: 4815469 (1989-03-01), Cohen et al.
patent: 4820399 (1989-04-01), Senda et al.
patent: 4822337 (1989-04-01), Newhouse et al.
patent: RE32922 (1989-05-01), Levin et al.
patent: 4830959 (1989-05-01), McNeil et al.
patent: 4832797 (1989-05-01), Vadgama et al.
patent: RE32947 (1989-06-01), Dormer et al.
patent: 4840893 (1989-06-01), Hill et al.
patent: 4848351 (1989-07-01), Finch
patent: 4871351 (1989-10-01), Feingold
patent: 4871440 (1989-10-01), Nagata et al.
patent: 4874500 (1989-10-01), Madou et al.
patent: 4890620 (1990-01-01), Gough
patent: 4894137 (1990-01-01), Takizawa et al.
patent: 4895147 (1990-01-01), Bodicky et al.
patent: 4895479 (1990-01-01), Michaelsen et al.
patent: 4897162 (1990-01-01), Lewandowski et al.
patent: 4897173 (1990-01-01), Nankai et al.
patent: 4909908 (1990-03-01), Ross et al.
patent: 4911794 (1990-03-01), Parce et al.
patent: 4917274 (1990-04-01), Asa et al.
patent: 4917800 (1990-04-01), Lonsdale et al.
patent: 4919141 (1990-04-01), Zier et al.
patent: 4919767 (1990-04-01), Vadgama et al.
patent: 4923586 (1990-05-01), Katayama et al.
patent: 4927516 (1990-05-01), Yamaguchi et al.
patent: 4934369 (1990-06-01), Maxwell
patent: 4935105 (1990-06-01), Churchouse
patent: 4935345 (1990-06-01), Guilbeau et al.
patent: 4936956 (1990-06-01), Wrighton
patent: 4938860 (1990-07-01), Wogoman
patent: 4942127 (1990-07-01), Wada et al.
patent: 4944299 (1990-07-01), Silvian
patent: 4945045 (1990-07-01), Forrest et al.
patent: 4950378 (1990-08-01), Nagata
patent: 4953552 (1990-09-01), DeMarzo
patent: 4954129 (1990-09-01), Giuliani et al.
patent: 4968400 (1990-11-01), Shimomura et al.
patent: 4969468 (1990-11-01), Byers et al.
patent: 4970145 (1990-11-01), Bennetto et al.
patent: 4974929 (1990-12-01), Curry
patent: 4986271 (1991-01-01), Wilkins
patent: 4994167 (1991-02-01), Shults et al.
patent: 5001054 (1991-03-01), Wagner
patent: 5025798 (1991-06-01), Schindele
patent: 5034192 (1991-07-01), Wrighton et al.
patent: 5037527 (19
Feldman Benjamin J.
Heller Adam
Say James
Vreeke Mark S.
Abbott Diabetes Care Inc.
Alcamo Elizabeth A.
Baba Edward J.
Bozicevic Field & Francis LLP
Noguerola Alex
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