Small molecule modulators of hepatocyte growth factor...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S365700

Reexamination Certificate

active

10740708

ABSTRACT:
The present invention provides compounds having formula (I):and pharmaceutically acceptable derivatives thereof, wherein R1, R2and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.

REFERENCES:
patent: 5997868 (1999-12-01), Goldberg et al.
patent: 6432406 (2002-08-01), Goldberg et al.
patent: 6589997 (2003-07-01), Pillarisetti et al.
patent: 6610726 (2003-08-01), Pillarisetti et al.
patent: 6855728 (2005-02-01), Pillarisetti et al.
patent: 2003/0022924 (2003-01-01), Pillarisetti et al.
patent: 2003/0045559 (2003-03-01), Pillarisetti et al.
patent: 2003/0216459 (2003-11-01), Pillarisetti et al.
patent: 2005/0113369 (2005-05-01), Zembower et al.
patent: 48 000713 (1973-01-01), None
patent: 02-193994 (1990-07-01), None
patent: 11-288112 (1999-10-01), None
patent: WO 01/02369 (2001-01-01), None
patent: WO 02/02593 (2002-01-01), None
patent: WO 02/02593 (2002-01-01), None
patent: WO 2004/009599 (2004-01-01), None
Anzaldi, et al., “Synthesis and antimicrobial activity of heterocyclic ionone-like derivatives”,Eur. J. Med. Chem., 34: 837-842, 1999.
Invitation to Pay Additional Fees for related application No. PCT/US2003/040917.
Perevalov, et al., “Spectroscopic features of isomeric trans-styrylpyrazoles”,Khimiya Geterotsiklicheskikh Soedinenii, 1990, 8:1061-1064.
Attaby et al., “Reactions with Cyanothioacetamide and its Derivatives: Synthesis and Reactions of Several New Thieno- and Azolopyridine Derivatives”Phosphorus, Sulfur, Silicon and the Related Elements, 119, 1-10, 1996.
Boekelheide et al., “Syntheses of Fused Aromatic Heterocycles by 1,3-Dipolar Addition Reactions. 3-Azapyrrocolines”Journal of Organic Chemistry, 33(5), 2062-4, 1968.
Eldin et al., “Reactions with Cyanothioacetamide Derivatives: Systhesis and Reactions of Some Pyridine and Annelated Pyridine Derivatives”Egypt. J Pharm Sci, 34(4-6), 805-815, 1993.
Elghandour et al., “A Facile Sythesis of Pyrazolo [1,5-a]pyridine Derivatives: Reaction of Cinnamonitriles with 5-Amino-4-cyano-3-cyanomethlypyrazole”J. Prakt. Chem., 330(4), 657-660, 1988.
Rateb, Iet al., “Reactions of Hydroxymethylene Ketones. Part II, Other Routes for the Preparation of Isoxazoles and Pyrazoles”Journal of the Chemical Society(C), 17, 2137-9, 1968.
Schneider, et al., “Facile Synthesis of Cyclopropyl Alkadienes”Angewandte Chemie, 91(3), 231-234, 1979.
Sottofatori, et al., “Synthesis of New Heterocyclic Derivatives of Retinoids”Journal of Heterocyclic Chemistry, 35(6), 1377-1380, 1998.
Subramaniam, et al., “Nonlinear Optic Properties of Heterocyclic Compounds Hyperpolarizability-structure Correlation”Ferroelectrics and related materials, 122(1-4), 229-38, 1991.
Tsuruta, et al., “Isolation of a Potential Intermediate Leading to 9-Phenylbicyclo[4.2.1]nona-2,4,7-triene in the Thermal Decomposition of α-Phenyl-α-tropylacetoaldehyde Tosylhydrazone”Journal of the American Chemical Society, 90(25), 7167-8, 1968.
Tsuruta, et al., “β-(2,4,6-Cycloheptatrien-1-yl)ethylcarbene. The Synthesis of 9-Substituted bicyclo[4.2.1]nona-2,4,7-trienes and 9-Substituted Barbaralanes”Bulletin of the Chem. Soc. Of Japan, 45, 2822-2828, 1972.

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